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Nonadherence to Medication in Inflammatory Bowel Disease: Rate and Reasons

BACKGROUND This study is the first study to evaluate the nonadherence rate and reasons of same patient with inflammatory bowel disease (IBD) in Iran. METHODS During 9 months, 500 patients with IBD were enrolled in the study. Patients were interviewed about their nonadherence behaviors. Factor analys...

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Autores principales: Ghadir, Mohammad Reza, Bagheri, Mohammad, Vahedi, Homayoon, Ebrahimi Daryani, Nasser, Malekzadeh, Reza, Hormati, Ahmad, Kolahdoozan, Shadi, Chaharmahali, Meghedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Association of Gastroerterology and Hepatology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885610/
https://www.ncbi.nlm.nih.gov/pubmed/27252818
http://dx.doi.org/10.15171/mejdd.2016.16
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author Ghadir, Mohammad Reza
Bagheri, Mohammad
Vahedi, Homayoon
Ebrahimi Daryani, Nasser
Malekzadeh, Reza
Hormati, Ahmad
Kolahdoozan, Shadi
Chaharmahali, Meghedi
author_facet Ghadir, Mohammad Reza
Bagheri, Mohammad
Vahedi, Homayoon
Ebrahimi Daryani, Nasser
Malekzadeh, Reza
Hormati, Ahmad
Kolahdoozan, Shadi
Chaharmahali, Meghedi
author_sort Ghadir, Mohammad Reza
collection PubMed
description BACKGROUND This study is the first study to evaluate the nonadherence rate and reasons of same patient with inflammatory bowel disease (IBD) in Iran. METHODS During 9 months, 500 patients with IBD were enrolled in the study. Patients were interviewed about their nonadherence behaviors. Factor analysis was used to analyze the collected answers. RESULTS The overall rate of nonadherence was 33.3% (27.6% intentional nonadherence and 5.7% unintentional nonadherence). 33.6% of the patients had at least one relapse after discontinuing treatment. The most frequent reason for intentional nonadherence was discontinuing the treatment after recovering from symptoms (42.7%). The most frequent reason for unintentional nonadherence was forgetfulness (5.2%). 19.8% of the patients did not visit their gastroenterologist on time and they purchased drugs from the drugstore. These patients reported that their clinics were too far and difficult to access. There was no significant relationship between nonadherence and demographic variables. CONCLUSION Multiple reasons are suggested as factors of medication nonadherence and they seem to be different among different populations. Determining these possible reasons, could lead to finding suitable strategies to overcome or reduce them.
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spelling pubmed-48856102016-06-01 Nonadherence to Medication in Inflammatory Bowel Disease: Rate and Reasons Ghadir, Mohammad Reza Bagheri, Mohammad Vahedi, Homayoon Ebrahimi Daryani, Nasser Malekzadeh, Reza Hormati, Ahmad Kolahdoozan, Shadi Chaharmahali, Meghedi Middle East J Dig Dis Original Article BACKGROUND This study is the first study to evaluate the nonadherence rate and reasons of same patient with inflammatory bowel disease (IBD) in Iran. METHODS During 9 months, 500 patients with IBD were enrolled in the study. Patients were interviewed about their nonadherence behaviors. Factor analysis was used to analyze the collected answers. RESULTS The overall rate of nonadherence was 33.3% (27.6% intentional nonadherence and 5.7% unintentional nonadherence). 33.6% of the patients had at least one relapse after discontinuing treatment. The most frequent reason for intentional nonadherence was discontinuing the treatment after recovering from symptoms (42.7%). The most frequent reason for unintentional nonadherence was forgetfulness (5.2%). 19.8% of the patients did not visit their gastroenterologist on time and they purchased drugs from the drugstore. These patients reported that their clinics were too far and difficult to access. There was no significant relationship between nonadherence and demographic variables. CONCLUSION Multiple reasons are suggested as factors of medication nonadherence and they seem to be different among different populations. Determining these possible reasons, could lead to finding suitable strategies to overcome or reduce them. Iranian Association of Gastroerterology and Hepatology 2016-04 /pmc/articles/PMC4885610/ /pubmed/27252818 http://dx.doi.org/10.15171/mejdd.2016.16 Text en © 2016 Middle East Journal of Digestive Diseases This work is published by Middle East Journal of Digestive Diseases as an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-sa/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Original Article
Ghadir, Mohammad Reza
Bagheri, Mohammad
Vahedi, Homayoon
Ebrahimi Daryani, Nasser
Malekzadeh, Reza
Hormati, Ahmad
Kolahdoozan, Shadi
Chaharmahali, Meghedi
Nonadherence to Medication in Inflammatory Bowel Disease: Rate and Reasons
title Nonadherence to Medication in Inflammatory Bowel Disease: Rate and Reasons
title_full Nonadherence to Medication in Inflammatory Bowel Disease: Rate and Reasons
title_fullStr Nonadherence to Medication in Inflammatory Bowel Disease: Rate and Reasons
title_full_unstemmed Nonadherence to Medication in Inflammatory Bowel Disease: Rate and Reasons
title_short Nonadherence to Medication in Inflammatory Bowel Disease: Rate and Reasons
title_sort nonadherence to medication in inflammatory bowel disease: rate and reasons
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885610/
https://www.ncbi.nlm.nih.gov/pubmed/27252818
http://dx.doi.org/10.15171/mejdd.2016.16
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