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Melanocortin 1 Receptor: Structure, Function, and Regulation

The melanocortin 1 receptor (MC1R) is a melanocytic G(s) protein coupled receptor that regulates skin pigmentation, UV responses, and melanoma risk. It is a highly polymorphic gene, and loss of function correlates with a fair, UV-sensitive, and melanoma-prone phenotype due to defective epidermal mel...

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Detalles Bibliográficos
Autores principales:	Wolf Horrell, Erin M., Boulanger, Mary C., D’Orazio, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885833/ https://www.ncbi.nlm.nih.gov/pubmed/27303435 http://dx.doi.org/10.3389/fgene.2016.00095

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