There and back again: insulin, ENaC, and the cortical collecting duct

Cell culture models suggest mechanisms by which insulin stimulates ENaC in the cortical collecting duct. These mechanisms still need to be tested for physiological significance in animal models of insulin resistance.[Image: see text]

Detalles Bibliográficos
Autor principal: Pao, Alan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886174/
https://www.ncbi.nlm.nih.gov/pubmed/27233302
http://dx.doi.org/10.14814/phy2.12809
Descripción
Sumario:Cell culture models suggest mechanisms by which insulin stimulates ENaC in the cortical collecting duct. These mechanisms still need to be tested for physiological significance in animal models of insulin resistance.[Image: see text]

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