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There and back again: insulin, ENaC, and the cortical collecting duct
Cell culture models suggest mechanisms by which insulin stimulates ENaC in the cortical collecting duct. These mechanisms still need to be tested for physiological significance in animal models of insulin resistance.[Image: see text]
Autor principal: | |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886174/ https://www.ncbi.nlm.nih.gov/pubmed/27233302 http://dx.doi.org/10.14814/phy2.12809 |
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author | Pao, Alan C. |
author_facet | Pao, Alan C. |
author_sort | Pao, Alan C. |
collection | PubMed |
description | Cell culture models suggest mechanisms by which insulin stimulates ENaC in the cortical collecting duct. These mechanisms still need to be tested for physiological significance in animal models of insulin resistance.[Image: see text] |
format | Online Article Text |
id | pubmed-4886174 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-48861742016-08-17 There and back again: insulin, ENaC, and the cortical collecting duct Pao, Alan C. Physiol Rep Editorial Cell culture models suggest mechanisms by which insulin stimulates ENaC in the cortical collecting duct. These mechanisms still need to be tested for physiological significance in animal models of insulin resistance.[Image: see text] John Wiley and Sons Inc. 2016-05-27 /pmc/articles/PMC4886174/ /pubmed/27233302 http://dx.doi.org/10.14814/phy2.12809 Text en © 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Editorial Pao, Alan C. There and back again: insulin, ENaC, and the cortical collecting duct |
title | There and back again: insulin, ENaC, and the cortical collecting duct |
title_full | There and back again: insulin, ENaC, and the cortical collecting duct |
title_fullStr | There and back again: insulin, ENaC, and the cortical collecting duct |
title_full_unstemmed | There and back again: insulin, ENaC, and the cortical collecting duct |
title_short | There and back again: insulin, ENaC, and the cortical collecting duct |
title_sort | there and back again: insulin, enac, and the cortical collecting duct |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886174/ https://www.ncbi.nlm.nih.gov/pubmed/27233302 http://dx.doi.org/10.14814/phy2.12809 |
work_keys_str_mv | AT paoalanc thereandbackagaininsulinenacandthecorticalcollectingduct |