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Assessment of polygenic effects links primary open-angle glaucoma and age-related macular degeneration
Primary open-angle glaucoma (POAG) and age-related macular degeneration (AMD) are leading causes of irreversible blindness. Several loci have been mapped using genome-wide association studies. Until very recently, there was no recognized overlap in the genetic contribution to AMD and POAG. At genome...
Autores principales: | Cuellar-Partida, Gabriel, Craig, Jamie E., Burdon, Kathryn P., Wang, Jie Jin, Vote, Brendan J., Souzeau, Emmanuelle, McAllister, Ian L., Isaacs, Timothy, Lake, Stewart, Mackey, David A., Constable, Ian J., Mitchell, Paul, Hewitt, Alex W., MacGregor, Stuart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886254/ https://www.ncbi.nlm.nih.gov/pubmed/27241461 http://dx.doi.org/10.1038/srep26885 |
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