Exogenous NAD(+) decreases oxidative stress and protects H(2)O(2)-treated RPE cells against necrotic death through the up-regulation of autophagy

Increased oxidative stress, which can lead to the retinal pigment epithelium (RPE) cell death by inducing ATP depletion and DNA repair, is believed to be a prominent pathology in age-related macular degeneration (AMD). In the present study, we showed that and 0.1 mM nicotinamide adenine dinucleotide...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Zhao, Ke-ke, Tong, Yao, Zhou, Ya-li, Wang, Yi-xiao, Zhao, Pei-quan, Wang, Zhao-yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886526/
https://www.ncbi.nlm.nih.gov/pubmed/27240523
http://dx.doi.org/10.1038/srep26322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886526/
https://www.ncbi.nlm.nih.gov/pubmed/27240523
http://dx.doi.org/10.1038/srep26322

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