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Exogenous NAD(+) decreases oxidative stress and protects H(2)O(2)-treated RPE cells against necrotic death through the up-regulation of autophagy
Increased oxidative stress, which can lead to the retinal pigment epithelium (RPE) cell death by inducing ATP depletion and DNA repair, is believed to be a prominent pathology in age-related macular degeneration (AMD). In the present study, we showed that and 0.1 mM nicotinamide adenine dinucleotide...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886526/ https://www.ncbi.nlm.nih.gov/pubmed/27240523 http://dx.doi.org/10.1038/srep26322 |