Early pancreatic islet fate and maturation is controlled through RBP-Jκ

Notch signaling is known to control early pancreatic differentiation through Ngn3 repression. In later stages, downstream of Notch, the Presenilins are still required to maintain the endocrine fate allocation. Amongst their multiple targets, it remains unclear which one actually controls the mainten...

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Detalles Bibliográficos
Autores principales: Cras-Méneur, Corentin, Conlon, Megan, Zhang, Yaqing, Pasca Di Magliano, Marina, Bernal-Mizrachi, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886527/
https://www.ncbi.nlm.nih.gov/pubmed/27240887
http://dx.doi.org/10.1038/srep26874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886527/
https://www.ncbi.nlm.nih.gov/pubmed/27240887
http://dx.doi.org/10.1038/srep26874

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