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Global methylation, oxidative stress, and relative telomere length in biliary atresia patients

Alu and LINE-1 elements are retrotransposons with a ubiquitous presence in the human genome that can cause genomic instability, specifically relating to telomere length. Genotoxic agents may induce methylation of retrotransposons, in addition to oxidative DNA damage in the form of 8-hydroxy-2′-deoxy...

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Detalles Bibliográficos
Autores principales: Udomsinprasert, Wanvisa, Kitkumthorn, Nakarin, Mutirangura, Apiwat, Chongsrisawat, Voranush, Poovorawan, Yong, Honsawek, Sittisak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886632/
https://www.ncbi.nlm.nih.gov/pubmed/27243754
http://dx.doi.org/10.1038/srep26969