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Unmasking Upstream Gene Expression Regulators with miRNA-corrected mRNA Data

Expressed micro-RNA (miRNA) affects messenger RNA (mRNA) abundance, hindering the accuracy of upstream regulator analysis. Our objective was to provide an algorithm to correct such bias. Large mRNA and miRNA analyses were performed on RNA extracted from bovine liver and mammary tissue. Using four le...

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Detalles Bibliográficos
Autores principales: Bollmann, Stephanie, Bu, Dengpan, Wang, Jiaqi, Bionaz, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886696/
https://www.ncbi.nlm.nih.gov/pubmed/27279737
http://dx.doi.org/10.4137/BBI.S29332