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HMGB1 Induces Secretion of Matrix Vesicles by Macrophages to Enhance Ectopic Mineralization

Numerous clinical conditions have been linked to ectopic mineralization (EM). This process of pathological biomineralization is complex and not fully elucidated, but thought to be started within matrix vesicles (MVs). We hypothesized that high mobility group box 1 (HMGB1), a cytokine associated with...

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Detalles Bibliográficos
Autores principales: Chen, Qiang, Bei, Jun-Jie, Liu, Chuan, Feng, Shi-Bin, Zhao, Wei-Bo, Zhou, Zhou, Yu, Zheng-Ping, Du, Xiao-Jun, Hu, Hou-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887028/
https://www.ncbi.nlm.nih.gov/pubmed/27243975
http://dx.doi.org/10.1371/journal.pone.0156686