Cargando…

Silica nanoparticles induce reversible damage of spermatogenic cells via RIPK1 signal pathways in C57 mice

The reproductive toxicity of silica nanoparticles (SiNPs) is well known, but the underlying mechanism is still not clear. To investigate the toxic mechanism of SiNPs on spermatogenic cells, 60 C57 male mice were randomly and equally divided into three groups (the control group, the saline control gr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Lihua, Zhang, Jin, Zou, Yang, Zhang, Lianshuang, Wei, Jialiu, Shi, Zhixiong, Li, Yanbo, Guo, Caixia, Sun, Zhiwei, Zhou, Xianqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887058/ https://www.ncbi.nlm.nih.gov/pubmed/27307728 http://dx.doi.org/10.2147/IJN.S102268

Ejemplares similares

Exposure to Silica Nanoparticles Causes Reversible Damage of the Spermatogenic Process in Mice
por: Xu, Ying, et al.
Publicado: (2014)

Macrophages participate in local and systemic inflammation induced by amorphous silica nanoparticles through intratracheal instillation
por: Yang, Man, et al.
Publicado: (2016)

Toxic Effect of Silica Nanoparticles on Endothelial Cells through DNA Damage Response via Chk1-Dependent G2/M Checkpoint
por: Duan, Junchao, et al.
Publicado: (2013)

Toxic Effects of Silica Nanoparticles on Zebrafish Embryos and Larvae
por: Duan, Junchao, et al.
Publicado: (2013)

Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling
por: Guo, Caixia, et al.
Publicado: (2015)

Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling
por: Guo, Caixia, et al.
Publicado: (2016)

Oxidative Damage and Energy Metabolism Disorder Contribute to the Hemolytic Effect of Amorphous Silica Nanoparticles
por: Jiang, Lizhen, et al.
Publicado: (2016)

Protection of rat spermatogenic epithelium from damage induced by procarbazine chemotherapy.
por: Glode, L. M., et al.
Publicado: (1990)

Changes in Expressions of Spermatogenic Marker Genes and Spermatogenic Cell Population Caused by Stress
por: Tian, Pengxiang, et al.
Publicado: (2021)

Silica nanoparticles induce autophagy dysfunction via lysosomal impairment and inhibition of autophagosome degradation in hepatocytes
por: Wang, Ji, et al.
Publicado: (2017)

DNA Hypermethylation of CREB3L1 and Bcl-2 Associated with the Mitochondrial-Mediated Apoptosis via PI3K/Akt Pathway in Human BEAS-2B Cells Exposure to Silica Nanoparticles
por: Zou, Yang, et al.
Publicado: (2016)

Silica nanoparticles enhance autophagic activity, disturb endothelial cell homeostasis and impair angiogenesis
por: Duan, Junchao, et al.
Publicado: (2014)

Relative safety of various spermatogenic stem cell purification methods for application in spermatogenic stem cell transplantation
por: Tian, Jia, et al.
Publicado: (2019)

Evaluating the role of silver nanoparticles on acrosomal reaction and spermatogenic cells in rat
por: Miresmaeili, Sayyed Mohsen, et al.
Publicado: (2013)

Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress
por: Abulikemu, Alimire, et al.
Publicado: (2022)

ALDH Enzyme Expression Is Independent of the Spermatogenic Cycle, and Their Inhibition Causes Misregulation of Murine Spermatogenic Processes
por: Kent, Travis, et al.
Publicado: (2015)

Low-Dose Exposure of Silica Nanoparticles Induces Neurotoxicity via Neuroactive Ligand–Receptor Interaction Signaling Pathway in Zebrafish Embryos
por: Wei, Jialiu, et al.
Publicado: (2020)

Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice
por: Yu, Yang, et al.
Publicado: (2013)

Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis
por: Liu, Shuo, et al.
Publicado: (2018)

Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE(−/−) mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage
por: Ma, Ru, et al.
Publicado: (2020)

Shikonin-induced necroptosis in nasopharyngeal carcinoma cells via ROS overproduction and upregulation of RIPK1/RIPK3/MLKL expression
por: Liu, Tiancong, et al.
Publicado: (2019)

Amorphous silica nanoparticles cause abnormal cytokinesis and multinucleation through dysfunction of the centralspindlin complex and microfilaments
por: Xiao, Liyan, et al.
Publicado: (2023)

Computer simulations of the mouse spermatogenic cycle
por: Ray, Debjit, et al.
Publicado: (2014)

Multinucleation and cell dysfunction induced by amorphous silica nanoparticles in an L-02 human hepatic cell line
por: Wang, Wen, et al.
Publicado: (2013)

Involvement of lncRNA-HOTTIP in the Repair of Ultraviolet Light-Induced DNA Damage in Spermatogenic Cells
por: Liang, Meng, et al.
Publicado: (2019)

The Role of RIPK1 and RIPK3 in Cardiovascular Disease
por: DeRoo, Elise, et al.
Publicado: (2020)

UDP-glucuronate metabolism controls RIPK1-driven liver damage in nonalcoholic steatohepatitis
por: Zhang, Tao, et al.
Publicado: (2023)

Protocol for isolation and proteostatic analysis of sub-populations of spermatogenic cells in mouse
por: Zou, Qianxing, et al.
Publicado: (2022)

Ripk1 and haematopoiesis: a case for LUBAC and Ripk3
por: Annibaldi, Alessandro, et al.
Publicado: (2018)

Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway
por: Duan, Junchao, et al.
Publicado: (2014)

Behavioural and spermatogenic hybrid male breakdown in Nasonia
por: Clark, Michael E., et al.
Publicado: (2010)

Transcriptome research on spermatogenic molecular drive in mammals
por: Zhu, Zi-Jue, et al.
Publicado: (2015)

The Fate of Leydig Cells in Men with Spermatogenic Failure
por: Adamczewska, Daria, et al.
Publicado: (2022)

Diverse monogenic subforms of human spermatogenic failure
por: Nagirnaja, Liina, et al.
Publicado: (2022)

Silica nanoparticles induce liver fibrosis via TGF-β(1)/Smad3 pathway in ICR mice
por: Yu, Yang, et al.
Publicado: (2017)

TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3
por: Dowling, John P., et al.
Publicado: (2019)

Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis
por: Farooq, Muhammad, et al.
Publicado: (2019)

RIPK1 and RIPK3 inhibitors: potential weapons against inflammation to treat diabetic complications
por: Ke, Dan, et al.
Publicado: (2023)

Long noncoding RNAs regulated spermatogenesis in varicocele‐induced spermatogenic dysfunction
por: Wang, Shangren, et al.
Publicado: (2022)

Effect of Moxibustion on Testosterone Secretion and Apoptosis of Spermatogenic Cells in Aging Rats
por: Yao, Chongjie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_b9tfkvvion3tbv8afdho9coa4d