Sulfasalazine inhibits inflammation and fibrogenesis in pancreas via NF-κB signaling pathway in rats with oxidative stress-induced pancreatic injury

BACKGROUND: Pathogenesis and effective therapeutics of chronic pancreatic inflammation and fibrosis remain uncertain. PURPOSE: To investigate the effects of sulfasalazine (SF) on pancreatic inflammation and fibrogenesis. METHODS: Chronic pancreatic injury in rats was induced by diethyldithiocarbamat...

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Detalles Bibliográficos
Autores principales: Wang, Ya-Ru, Tian, Fei-Long, Yan, Ming-Xian, Fan, Jin-Hua, Wang, Li-Yun, Kuang, Rong-Guang, Li, Yan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887069/
https://www.ncbi.nlm.nih.gov/pubmed/27307705
http://dx.doi.org/10.2147/DDDT.S107679

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