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Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias

Porphyrias are disorders of heme metabolism frequently characterized by extreme photosensitivity. This symptom results from accumulation of porphyrins, tetrapyrrole intermediates in heme biosynthesis that generate reactive oxygen species when exposed to light, in the skin of affected individuals. He...

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Detalles Bibliográficos
Autores principales:	Stubenhaus, Bradford M, Dustin, John P, Neverett, Emily R, Beaudry, Megan S, Nadeau, Leanna E, Burk-McCoy, Ethan, He, Xinwen, Pearson, Bret J, Pellettieri, Jason
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887210/ https://www.ncbi.nlm.nih.gov/pubmed/27240733 http://dx.doi.org/10.7554/eLife.14175

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