Robust transcriptome-wide discovery of RNA binding protein binding sites with enhanced CLIP (eCLIP)

As RNA binding proteins (RBPs) play essential roles in cellular physiology by interacting with target RNAs, binding site identification by UV-crosslinking and immunoprecipitation (CLIP) of ribonucleoprotein complexes is critical to understanding RBP function. However, current CLIP protocols are tech...

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Detalles Bibliográficos
Autores principales: Van Nostrand, Eric L., Pratt, Gabriel A., Shishkin, Alexander A., Gelboin-Burkhart, Chelsea, Fang, Mark Y., Sundararaman, Balaji, Blue, Steven M., Nguyen, Thai B., Surka, Christine, Elkins, Keri, Stanton, Rebecca, Rigo, Frank, Guttman, Mitchell, Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887338/
https://www.ncbi.nlm.nih.gov/pubmed/27018577
http://dx.doi.org/10.1038/nmeth.3810

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