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Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma

Increasing evidence demonstrates the immunosuppressive kynurenine pathway’s (KP) role in the pathophysiology of human gliomas. To study the KP in vivo, we used the noninvasive molecular imaging tracer α-[(11)C]-methyl-l-tryptophan (AMT). The AMT-positron emission tomography (PET) has shown high upta...

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Detalles Bibliográficos
Autores principales:	Guastella, Anthony R., Michelhaugh, Sharon K., Klinger, Neil V., Kupsky, William J., Polin, Lisa A., Muzik, Otto, Juhász, Csaba, Mittal, Sandeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887573/ https://www.ncbi.nlm.nih.gov/pubmed/27151136 http://dx.doi.org/10.1177/1536012116644881

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