Efficacy of Mitochondrial Antioxidant Plastoquinonyl-decyl-triphenylphosphonium Bromide (SkQ1) in the Rat Model of Autoimmune Arthritis

Rheumatoid arthritis is one of the most common autoimmune diseases. Many antioxidants have been tested in arthritis, but their efficacy was, at best, marginal. In this study, a novel mitochondria-targeted antioxidant, plastoquinonyl-decyl-triphenylphosphonium bromide (SkQ1), was tested in vivo to pr...

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Detalles Bibliográficos
Autores principales: Andreev-Andrievskiy, Alexander A., Kolosova, Nataliya G., Stefanova, Natalia A., Lovat, Maxim V., Egorov, Maxim V., Manskikh, Vasily N., Zinovkin, Roman A., Galkin, Ivan I., Prikhodko, Anastasia S., Skulachev, Maxim V., Lukashev, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887630/
https://www.ncbi.nlm.nih.gov/pubmed/27293517
http://dx.doi.org/10.1155/2016/8703645

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