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Deposition of BACE-1 Protein in the Brains of APP/PS1 Double Transgenic Mice

The main causes of Alzheimer's disease remain elusive. Previous data have implicated the BACE-1 protein as a central player in the pathogenesis of Alzheimer's disease. However, many inhibitors of BACE-1 have failed during preclinical and clinical trials for AD treatment. Therefore, uncover...

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Detalles Bibliográficos
Autores principales:	Luo, Gang, Xu, Hongxia, Huang, Yinuo, Mo, Dapeng, Song, Ligang, Jia, Baixue, Wang, Bo, Jin, Zhanqiang, Miao, Zhongrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887654/ https://www.ncbi.nlm.nih.gov/pubmed/27294139 http://dx.doi.org/10.1155/2016/8380618

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