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A synthetic kisspeptin analog that triggers ovulation and advances puberty

The neuropeptide kisspeptin and its receptor, KiSS1R, govern the reproductive timeline of mammals by triggering puberty onset and promoting ovulation by stimulating gonadotrophin-releasing hormone (GnRH) secretion. To overcome the drawback of kisspeptin short half-life we designed kisspeptin analogs...

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Detalles Bibliográficos
Autores principales: Decourt, C., Robert, V., Anger, K., Galibert, M., Madinier, J.-B., Liu, X., Dardente, H., Lomet, D., Delmas, A. F., Caraty, A., Herbison, A. E., Anderson, G. M, Aucagne, V., Beltramo, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887910/
https://www.ncbi.nlm.nih.gov/pubmed/27245315
http://dx.doi.org/10.1038/srep26908