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A synthetic kisspeptin analog that triggers ovulation and advances puberty
The neuropeptide kisspeptin and its receptor, KiSS1R, govern the reproductive timeline of mammals by triggering puberty onset and promoting ovulation by stimulating gonadotrophin-releasing hormone (GnRH) secretion. To overcome the drawback of kisspeptin short half-life we designed kisspeptin analogs...
Autores principales: | Decourt, C., Robert, V., Anger, K., Galibert, M., Madinier, J.-B., Liu, X., Dardente, H., Lomet, D., Delmas, A. F., Caraty, A., Herbison, A. E., Anderson, G. M, Aucagne, V., Beltramo, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887910/ https://www.ncbi.nlm.nih.gov/pubmed/27245315 http://dx.doi.org/10.1038/srep26908 |
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