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Considerations for a European animal welfare standard to evaluate adverse phenotypes in teleost fish

The EU Directive on the use animals in research requires scientists to assess and document pain, distress or lasting harm of genetically modified animals. This article proposes a detailed protocol and guidelines for assessing adverse phenotypes in teleost fish, an important model organism for biomed...

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Detalles Bibliográficos
Autores principales: Bert, Bettina, Chmielewska, Justyna, Bergmann, Sven, Busch, Maximilian, Driever, Wolfgang, Finger‐Baier, Karin, Hößler, Johanna, Köhler, Almut, Leich, Nora, Misgeld, Thomas, Nöldner, Torsten, Reiher, Annegret, Schartl, Manfred, Seebach‐Sproedt, Anja, Thumberger, Thomas, Schönfelder, Gilbert, Grune, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888240/
https://www.ncbi.nlm.nih.gov/pubmed/27107050
http://dx.doi.org/10.15252/embj.201694448
Descripción
Sumario:The EU Directive on the use animals in research requires scientists to assess and document pain, distress or lasting harm of genetically modified animals. This article proposes a detailed protocol and guidelines for assessing adverse phenotypes in teleost fish, an important model organism for biomedical research. [Image: see text]