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G1 Domain of Versican Regulates Hyaluronan Organization and the Phenotype of Cultured Human Dermal Fibroblasts

Variants of versican have wide-ranging effects on cell and tissue phenotype, impacting proliferation, adhesion, pericellular matrix composition, and elastogenesis. The G1 domain of versican, which contains two Link modules that bind to hyaluronan (HA), may be central to these effects. Recombinant hu...

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Detalles Bibliográficos
Autores principales: Merrilees, Mervyn J., Zuo, Ning, Evanko, Stephen P., Day, Anthony J., Wight, Thomas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888412/
https://www.ncbi.nlm.nih.gov/pubmed/27126822
http://dx.doi.org/10.1369/0022155416643913