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Ribosome quality control is a central protection mechanism for yeast exposed to deoxynivalenol and trichothecin

BACKGROUND: The trichothecene mycotoxins deoxynivalenol (DON) and trichothecin (TTC) are inhibitors of eukaryotic protein synthesis. Their effect on cellular homeostasis is poorly understood. We report a systematic functional investigation of the effect of DON and TTC on the yeast Saccharomyces cere...

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Detalles Bibliográficos
Autores principales: Kugler, Karl G., Jandric, Zeljkica, Beyer, Reinhard, Klopf, Eva, Glaser, Walter, Lemmens, Marc, Shams, Mehrdad, Mayer, Klaus, Adam, Gerhard, Schüller, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888481/
https://www.ncbi.nlm.nih.gov/pubmed/27245696
http://dx.doi.org/10.1186/s12864-016-2718-y