Investigation of MMP-1 genetic polymorphisms and protein expression and their effects on the risk of Kashin-Beck disease in the northwest Chinese Han population

BACKGROUND: The etiology of Kashin-Beck disease (KBD), an endemic osteochondropathy, is largely unknown. Matrix metalloproteinase-1 (MMP-1) plays a central role in the initiation and progression of cartilage destruction; however, no study has reported on the relationship between KBD and MMP-1. This...

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Detalles Bibliográficos
Autores principales: Shi, Xiaowei, Lv, Aili, Ma, Jing, Zhang, Feng, Wen, Yan, Zhang, Zengtie, Guo, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888510/
https://www.ncbi.nlm.nih.gov/pubmed/27245218
http://dx.doi.org/10.1186/s13018-016-0398-6

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