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Activated brain mast cells contribute to postoperative cognitive dysfunction by evoking microglia activation and neuronal apoptosis

BACKGROUND: Neuroinflammation plays a key role in the occurrence and development of postoperative cognitive dysfunction (POCD). Microglia, the resident immune cells in the brain, has been increasingly recognized to contribute to neuroinflammation. Although brain mast cells (MCs) are the “first respo...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiang, Dong, Hongquan, Li, Nana, Zhang, Susu, Sun, Jie, Zhang, Shu, Qian, Yanning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888609/ https://www.ncbi.nlm.nih.gov/pubmed/27245661 http://dx.doi.org/10.1186/s12974-016-0592-9

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