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Herbal formula GAPT prevents beta amyloid deposition induced Ca(2+)/Calmodulin-dependent protein kinase II and Ca(2+)/Calmodulin-dependent protein phosphatase 2B imbalance in APPV717I mice

BACKGROUND: Synaptic dysfunction is one of the pathological characteristics of Alzheimer's disease (AD), which is directly related to the progressive decline of cognitive function. CaMKII and CaN have been found to play important roles in memory processes and synaptic transmission. So present s...

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Detalles Bibliográficos
Autores principales: Shi, Jing, Zhang, Xuekai, Yin, Long, Wei, Mingqing, Ni, Jingnian, Li, Ting, Wang, Pengwen, Tian, Jinzhou, Wang, Yongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888629/
https://www.ncbi.nlm.nih.gov/pubmed/27245225
http://dx.doi.org/10.1186/s12906-016-1144-7