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Herbal formula GAPT prevents beta amyloid deposition induced Ca(2+)/Calmodulin-dependent protein kinase II and Ca(2+)/Calmodulin-dependent protein phosphatase 2B imbalance in APPV717I mice
BACKGROUND: Synaptic dysfunction is one of the pathological characteristics of Alzheimer's disease (AD), which is directly related to the progressive decline of cognitive function. CaMKII and CaN have been found to play important roles in memory processes and synaptic transmission. So present s...
Autores principales: | Shi, Jing, Zhang, Xuekai, Yin, Long, Wei, Mingqing, Ni, Jingnian, Li, Ting, Wang, Pengwen, Tian, Jinzhou, Wang, Yongyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888629/ https://www.ncbi.nlm.nih.gov/pubmed/27245225 http://dx.doi.org/10.1186/s12906-016-1144-7 |
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