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Liver cancer with concomitant TP53 and CTNNB1 mutations: a case report

BACKGROUND: In the spectrum of molecular alterations found in hepatocellular carcinoma (HCC), somatic mutations in the WNT/β-catenin pathway and the p53/cell cycle control pathway are among the most frequent ones. It has been suggested that both mutations occur in a mutually exclusive manner and the...

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Detalles Bibliográficos
Autores principales: Friemel, Juliane, Rechsteiner, Markus, Bawohl, Marion, Frick, Lukas, Müllhaupt, Beat, Lesurtel, Mickaël, Weber, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888639/
https://www.ncbi.nlm.nih.gov/pubmed/27252594
http://dx.doi.org/10.1186/s12907-016-0029-5