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Liver cancer with concomitant TP53 and CTNNB1 mutations: a case report
BACKGROUND: In the spectrum of molecular alterations found in hepatocellular carcinoma (HCC), somatic mutations in the WNT/β-catenin pathway and the p53/cell cycle control pathway are among the most frequent ones. It has been suggested that both mutations occur in a mutually exclusive manner and the...
Autores principales: | Friemel, Juliane, Rechsteiner, Markus, Bawohl, Marion, Frick, Lukas, Müllhaupt, Beat, Lesurtel, Mickaël, Weber, Achim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888639/ https://www.ncbi.nlm.nih.gov/pubmed/27252594 http://dx.doi.org/10.1186/s12907-016-0029-5 |
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