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Cross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancer

BACKGROUND: Tissue Factor (TF) forms a proteolytically active complex together with coagulation factor VIIa (FVIIa) and functions as the trigger of blood coagulation or alternatively activates cell signaling. We recently described that EphA2 of the Eph tyrosine kinase receptor family is cleaved dire...

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Detalles Bibliográficos
Autores principales: Eriksson, Oskar, Thulin, Åsa, Asplund, Anna, Hegde, Geeta, Navani, Sanjay, Siegbahn, Agneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888641/
https://www.ncbi.nlm.nih.gov/pubmed/27246245
http://dx.doi.org/10.1186/s12885-016-2375-1