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Molecular clock of HIV-1 envelope genes under early immune selection
BACKGROUND: The molecular clock hypothesis that genes or proteins evolve at a constant rate is a key tool to reveal phylogenetic relationships among species. Using the molecular clock, we can trace an infection back to transmission using HIV-1 sequences from a single time point. Whether or not a str...
Autores principales: | Park, Sung Yong, Love, Tanzy M. T., Perelson, Alan S., Mack, Wendy J., Lee, Ha Youn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888660/ https://www.ncbi.nlm.nih.gov/pubmed/27246201 http://dx.doi.org/10.1186/s12977-016-0269-6 |
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