Development of a dot blot assay with antibodies to recombinant “core” 14-3-3 protein: Evaluation of its usefulness in diagnosis of Creutzfeldt–Jakob disease

BACKGROUND AND PURPOSE: Definitive diagnosis of Creutzfeldt–Jakob disease (CJD) requires demonstration of infective prion protein (PrP(Sc)) in brain tissues by immunohistochemistry or immunoblot, making antemortem diagnosis of CJD difficult. The World Health Organization (WHO) recommends detection o...

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Detalles Bibliográficos
Autores principales: Subramanian, Sarada, Mahadevan, Anita, Satishchandra, Parthasarathy, Shankar, Susarla Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888683/
https://www.ncbi.nlm.nih.gov/pubmed/27293331
http://dx.doi.org/10.4103/0972-2327.176867

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