HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP

Some mitochondrial long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the mechanisms that mediate their transport to mitochondria are poorly characterized. Using affinity RNA pull-down followed by mass spectrometry analysis, we found two RNA-binding proteins (RBPs), HuR (human antigen R)...

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Detalles Bibliográficos
Autores principales: Noh, Ji Heon, Kim, Kyoung Mi, Abdelmohsen, Kotb, Yoon, Je-Hyun, Panda, Amaresh C., Munk, Rachel, Kim, Jiyoung, Curtis, Jessica, Moad, Christopher A., Wohler, Christina M., Indig, Fred E., de Paula, Wilson, Dudekula, Dawood B., De, Supriyo, Piao, Yulan, Yang, Xiaoling, Martindale, Jennifer L., de Cabo, Rafael, Gorospe, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888842/
https://www.ncbi.nlm.nih.gov/pubmed/27198227
http://dx.doi.org/10.1101/gad.276022.115

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