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Interferon‐beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization
Age‐related macular degeneration (AMD) is a leading cause of vision loss among the elderly. AMD pathogenesis involves chronic activation of the innate immune system including complement factors and microglia/macrophage reactivity in the retina. Here, we show that lack of interferon‐β signaling in th...
Autores principales: | Lückoff, Anika, Caramoy, Albert, Scholz, Rebecca, Prinz, Marco, Kalinke, Ulrich, Langmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888856/ https://www.ncbi.nlm.nih.gov/pubmed/27137488 http://dx.doi.org/10.15252/emmm.201505994 |
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