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Comparison of human coagulation factor VIII expression directed by cytomegalovirus and mammary gland-specific promoters in HC11 cells and transgenic mice

Hemophilia A is an inherited X-linked recessive bleeding disorder caused by coagulant factor VIII (FVIII) deficiency. The conventional treatment involves the administration of recombinant human FVIII (rhFVIII) preparations. In this study, the mammary gland ‘bioreactor’ is designed to specifically an...

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Detalles Bibliográficos
Autores principales:	Wang, Qing, Hao, Siguo, Ma, Liyuan, Zhang, Wenhao, Wan, Jiangbo, Deng, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams And Wilkins 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888922/ https://www.ncbi.nlm.nih.gov/pubmed/26192111 http://dx.doi.org/10.1097/MBC.0000000000000318

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