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LDL–cholesterol transport to the endoplasmic reticulum: current concepts

PURPOSE OF REVIEW: In this article, we summarize the present information related to the export of LDL-derived cholesterol from late endosomes, with a focus on Nieman-Pick disease, type C1 (NPC1) cholesterol delivery toward the endoplasmic reticulum (ER). We review data suggesting that several pathwa...

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Detalles Bibliográficos
Autores principales: Pfisterer, Simon G., Peränen, Johan, Ikonen, Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888931/
https://www.ncbi.nlm.nih.gov/pubmed/27054443
http://dx.doi.org/10.1097/MOL.0000000000000292