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Profile of Class I Histone Deacetylases (HDAC) by Human Dendritic Cells after Alcohol Consumption and In Vitro Alcohol Treatment and Their Implication in Oxidative Stress: Role of HDAC Inhibitors Trichostatin A and Mocetinostat

Epigenetic mechanisms have been shown to play a role in alcohol use disorders (AUDs) and may prove to be valuable therapeutic targets. However, the involvement of histone deacetylases (HDACs) on alcohol-induced oxidative stress of human primary monocyte-derived dendritic cells (MDDCs) has not been e...

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Detalles Bibliográficos
Autores principales: Agudelo, Marisela, Figueroa, Gloria, Parira, Tiyash, Yndart, Adriana, Muñoz, Karla, Atluri, Venkata, Samikkannu, Thangavel, Nair, Madhavan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889108/
https://www.ncbi.nlm.nih.gov/pubmed/27249803
http://dx.doi.org/10.1371/journal.pone.0156421