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Autophagy protects ovarian cancer-associated fibroblasts against oxidative stress

RNA-Seq and gene set enrichment anylysis revealed that ovarian cancer associated fibroblasts (CAFs) are mitotically active compared with normal fibroblasts (NFs). Cellular senescence is observed in CAFs treated with H(2)O(2) as shown by elevated SA-β-gal activity and p21 (WAF1/Cip1) protein levels....

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Detalles Bibliográficos
Autores principales:	Wang, Qian, Xue, Liang, Zhang, Xiaoyu, Bu, Shixia, Zhu, Xueliang, Lai, Dongmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889272/ https://www.ncbi.nlm.nih.gov/pubmed/27074587 http://dx.doi.org/10.1080/15384101.2016.1170269

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