Cargando…

Dynamics of Translation of Single mRNA Molecules In Vivo

Regulation of mRNA translation, the process by which ribosomes decode mRNAs into polypeptides, is used to tune cellular protein levels. Currently, methods for observing the complete process of translation from single mRNAs in vivo are unavailable. Here, we report the long-term (>1 hr) imaging of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Xiaowei, Hoek, Tim A., Vale, Ronald D., Tanenbaum, Marvin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889334/ https://www.ncbi.nlm.nih.gov/pubmed/27153498 http://dx.doi.org/10.1016/j.cell.2016.04.034

Ejemplares similares

Translation and Replication Dynamics of Single RNA Viruses
por: Boersma, Sanne, et al.
Publicado: (2020)

Regulation of mRNA translation during mitosis
por: Tanenbaum, Marvin E, et al.
Publicado: (2015)

Single-Molecule Imaging Uncovers Rules Governing Nonsense-Mediated mRNA Decay
por: Hoek, Tim A., et al.
Publicado: (2019)

Nonsense-mediated mRNA decay uses complementary mechanisms to suppress mRNA and protein accumulation
por: Udy, Dylan B, et al.
Publicado: (2021)

Imaging and Quantification of mRNA Molecules at Single-Cell Resolution in the Human Fungal Pathogen Candida albicans
por: Moreno-Velásquez, Sergio D., et al.
Publicado: (2021)

The mRNA-bound proteome of the early fly embryo
por: Wessels, Hans-Hermann, et al.
Publicado: (2016)

Cycloheximide can distort measurements of mRNA levels and translation efficiency
por: Santos, Daniel A, et al.
Publicado: (2019)

Mini-III RNase-based dual-color system for in vivo mRNA tracking
por: Zhang, Lin, et al.
Publicado: (2020)

Novel proteomic approach (PUNCH-P) reveals cell cycle-specific fluctuations in mRNA translation
por: Aviner, Ranen, et al.
Publicado: (2013)

Multi-Color Single-Molecule Imaging Uncovers Extensive Heterogeneity in mRNA Decoding
por: Boersma, Sanne, et al.
Publicado: (2019)

Selective translational control of cellular and viral mRNAs by RPS3 mRNA binding
por: Havkin-Solomon, Tal, et al.
Publicado: (2023)

mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells
por: Kubiura-Ichimaru, Musashi, et al.
Publicado: (2023)

Global 5′-UTR RNA structure regulates translation of a SERPINA1 mRNA
por: Grayeski, Philip J, et al.
Publicado: (2022)

Experimental reproducibility limits the correlation between mRNA and protein abundances in tumor proteomic profiles
por: Upadhya, Swathi Ramachandra, et al.
Publicado: (2022)

Single-molecule dynamics of nuclear mRNA
por: Shav-Tal, Yaron, et al.
Publicado: (2009)

Absolute Measurements of mRNA Translation in Caulobacter crescentus Reveal Important Fitness Costs of Vitamin B(12) Scavenging
por: Aretakis, James R., et al.
Publicado: (2019)

Single-molecule visualization of mRNA circularization during translation
por: Kim, Byungju, et al.
Publicado: (2023)

Phospho‐RNA‐seq: a modified small RNA‐seq method that reveals circulating mRNA and lncRNA fragments as potential biomarkers in human plasma
por: Giraldez, Maria D, et al.
Publicado: (2019)

Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics
por: Kotliar, Dylan, et al.
Publicado: (2020)

The C. elegans 3′ UTRome v2 resource for studying mRNA cleavage and polyadenylation, 3′-UTR biology, and miRNA targeting
por: Steber, Hannah S., et al.
Publicado: (2019)

RCSB Protein Data Bank resources for structure-facilitated design of mRNA vaccines for existing and emerging viral pathogens
por: Goodsell, David S., et al.
Publicado: (2022)

Effective and Rapid Generation of Functional Neutrophils from Induced Pluripotent Stem Cells Using ETV2-Modified mRNA
por: Brok-Volchanskaya, Vera S., et al.
Publicado: (2019)

Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring
por: Yeom, Kyu-Hyeon, et al.
Publicado: (2021)

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos
por: Petropoulos, Sophie, et al.
Publicado: (2016)

A comparative transcriptional landscape of maize and sorghum obtained by single-molecule sequencing
por: Wang, Bo, et al.
Publicado: (2018)

A framework to validate fluorescently labeled DNA-binding proteins for single-molecule experiments
por: Molina, Miranda, et al.
Publicado: (2023)

Dynamics of translation by single ribosomes through mRNA secondary structures
por: Chen, Chunlai, et al.
Publicado: (2013)

Time-resolved single-cell sequencing identifies multiple waves of mRNA decay during the mitosis-to-G1 phase transition
por: Krenning, Lenno, et al.
Publicado: (2022)

The Dynamics of Supply and Demand in mRNA Translation
por: Brackley, Chris A., et al.
Publicado: (2011)

High-Content Quantification of Single-Cell Immune Dynamics
por: Junkin, Michael, et al.
Publicado: (2016)

Single-molecule identification of the target RNAs of different RNA binding proteins simultaneously in cells
por: Flamand, Mathieu N., et al.
Publicado: (2022)

Dynamic changes in RNA–protein interactions and RNA secondary structure in mammalian erythropoiesis
por: Shan, Mengge, et al.
Publicado: (2021)

An ex vivo system to study cellular dynamics underlying mouse peri-implantation development
por: Ichikawa, Takafumi, et al.
Publicado: (2022)

Small RNA expression and miRNA modification dynamics in human oocytes and early embryos
por: Paloviita, Pauliina, et al.
Publicado: (2021)

Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes
por: Katz, Zachary B, et al.
Publicado: (2016)

Live imaging of mRNA using RNA-stabilized fluorogenic proteins
por: Wu, Jiahui, et al.
Publicado: (2019)

Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing
por: Shah, Sheel, et al.
Publicado: (2016)

GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors
por: Sriram, Krishna, et al.
Publicado: (2019)

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2
por: Humphrey, Sean J., et al.
Publicado: (2013)

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
por: Darmanis, Spyros, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2umirbu4o6arpir1pv0bk4nk64