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High density three-dimensional localization microscopy across large volumes

Extending three-dimensional (3D) single molecule localization microscopy away from the coverslip and into thicker specimens will greatly broaden its biological utility. However, localizing molecules in 3D with high precision in such samples, while simultaneously achieving the extreme labeling densit...

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Detalles Bibliográficos
Autores principales: Legant, Wesley R., Shao, Lin, Grimm, Jonathan B., Brown, Timothy A., Milkie, Daniel E., Avants, Brian B., Lavis, Luke D., Betzig, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889433/
https://www.ncbi.nlm.nih.gov/pubmed/26950745
http://dx.doi.org/10.1038/nmeth.3797

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