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High density three-dimensional localization microscopy across large volumes
Extending three-dimensional (3D) single molecule localization microscopy away from the coverslip and into thicker specimens will greatly broaden its biological utility. However, localizing molecules in 3D with high precision in such samples, while simultaneously achieving the extreme labeling densit...
Autores principales: | Legant, Wesley R., Shao, Lin, Grimm, Jonathan B., Brown, Timothy A., Milkie, Daniel E., Avants, Brian B., Lavis, Luke D., Betzig, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889433/ https://www.ncbi.nlm.nih.gov/pubmed/26950745 http://dx.doi.org/10.1038/nmeth.3797 |
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