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MIM REGULATES THE TRAFFICKING OF BONE MARROW CELLS VIA MODULATING SURFACE EXPRESSION OF CXCR4

Missing in metastasis (MIM) is abundantly expressed in hematopoietic cells. Here we characterized the impact of MIM deficiency on murine bone marrow (BM) cells. Although MIM(-/-) cells proliferated similarly to wild type (WT), they exhibited stronger response to chemokine SDF-1, increase in surface...

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Detalles Bibliográficos
Autores principales: Zhan, Tailan, Cao, Chunzhang, Li, Lushen, Gu, Ning, Civin, Curt I., Zhan, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889520/
https://www.ncbi.nlm.nih.gov/pubmed/26965284
http://dx.doi.org/10.1038/leu.2016.39