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Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans
Under adverse environmental conditions the nematode Caenorhabditis elegans can enter an alternate developmental stage called the dauer larva. To identify lipophilic signaling molecules that influence this process, we screened a library of bioactive lipids and found that AM251, an antagonist of the h...
Autores principales: | Reis Rodrigues, Pedro, Kaul, Tiffany K., Ho, Jo-Hao, Lucanic, Mark, Burkewitz, Kristopher, Mair, William B., Held, Jason M., Bohn, Laura M., Gill, Matthew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889665/ https://www.ncbi.nlm.nih.gov/pubmed/27172180 http://dx.doi.org/10.1534/g3.116.026997 |
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