CSF/plasma HIV-1 RNA discordance even at low levels is associated with up-regulation of host inflammatory mediators in CSF()

INTRODUCTION: HIV-1 RNA can be found at higher levels in cerebrospinal fluid (CSF) than in plasma, termed CSF/plasma discordance. The clinical significance of CSF/plasma discordance is not known and the degree of discordance considered important varies. We aimed to determine whether a panel of CSF c...

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Detalles Bibliográficos
Autores principales: Nightingale, Sam, Michael, Benedict D., Fisher, Martin, Winston, Alan, Nelson, Mark, Taylor, Steven, Ustianowski, Andrew, Ainsworth, Jonathan, Gilson, Richard, Haddow, Lewis, Ong, Edmund, Leen, Clifford, Minton, Jane, Post, Frank, Beloukas, Apostolos, Borrow, Ray, Pirmohamed, Munir, Geretti, Anna Maria, Khoo, Saye, Solomon, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889775/
https://www.ncbi.nlm.nih.gov/pubmed/27131579
http://dx.doi.org/10.1016/j.cyto.2016.04.004

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