Cargando…

An EP2 Agonist Facilitates NMDA-Induced Outward Currents and Inhibits Dendritic Beading through Activation of BK Channels in Mouse Cortical Neurons

Prostaglandin E(2) (PGE(2)), a major metabolite of arachidonic acid produced by cyclooxygenase pathways, exerts its bioactive responses by activating four E-prostanoid receptor subtypes, EP1, EP2, EP3, and EP4. PGE(2) enables modulating N-methyl-D-aspartate (NMDA) receptor-mediated responses. Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hayashi, Yoshinori, Morinaga, Saori, Liu, Xia, Zhang, Jing, Wu, Zhou, Yokoyama, Takeshi, Nakanishi, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889853/ https://www.ncbi.nlm.nih.gov/pubmed/27298516 http://dx.doi.org/10.1155/2016/5079597

Ejemplares similares

BK channels in microglia are required for morphine-induced hyperalgesia
por: Hayashi, Yoshinori, et al.
Publicado: (2016)

Lysine-Rich Extracellular Rings Formed by hβ2 Subunits Confer the Outward Rectification of BK Channels
por: Chen, Maorong, et al.
Publicado: (2008)

The NMDA Agonist D-Cycloserine Facilitates Fear Memory Consolidation in Humans
por: Kalisch, Raffael, et al.
Publicado: (2009)

Endogenous Modulators of NMDA Receptor Control Dendritic Field Expansion of Cortical Neurons
por: Jorratt, Pascal, et al.
Publicado: (2022)

The Outward Mindset
por: The Arbinger Institute
Publicado: (2019)

PM432. Evaluation of the extrapyramidal side effects (EPS) liability of NMDA receptor glycine-binding site agonists
por: Ohno, Yukihiro, et al.
Publicado: (2016)

NMDA receptor–BK channel coupling regulates synaptic plasticity in the barrel cortex
por: Gómez, Ricardo, et al.
Publicado: (2021)

Christmas "Outward and Visible"
Publicado: (1889)

Outward Luxation of the Femur
por: Wyman, W. E. A.
Publicado: (1897)

Activity-dependent modulation of NMDA receptors by endogenous zinc shapes dendritic function in cortical neurons
por: Morabito, Annunziato, et al.
Publicado: (2022)

Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca(2+)-Dependent Outward Rectification
por: Madry, Christian, et al.
Publicado: (2010)

Mental Derangement and Outward Surroundings
por: Good, P. H.
Publicado: (1890)

State-dependent inhibition of BK channels by the opioid agonist loperamide
por: Vouga, Alexandre G., et al.
Publicado: (2021)

Calcium-induced Transitions between the Spontaneous Miniature Outward and the Transient Outward Currents in Retinal Amacrine Cells
por: Mitra, Pratip, et al.
Publicado: (2002)

Curious Cases of Dislocation of the Patella Outwards
Publicado: (1829)

Mechanical stress activates NMDA receptors in the absence of agonists
por: Maneshi, Mohammad Mehdi, et al.
Publicado: (2017)

Anesthetic management of a patient with chromosome 6p duplication: a case report
por: Morinaga, Saori, et al.
Publicado: (2017)

Humanin Rescues Cultured Rat Cortical Neurons from NMDA-Induced Toxicity Not by NMDA Receptor
por: Cui, Ai-Ling, et al.
Publicado: (2014)

THE OUTWARD TRANSPORT OF CORTISOL BY MAMMALIAN CELLS IN VITRO
por: Gross, Stephen R., et al.
Publicado: (1970)

Relief of Pain by the Outward Application of Hydrate of Chloral
Publicado: (1877)

Report of a Case of Outward Dislocation of the Knee
por: Bennett, T. J.
Publicado: (1894)

Outward open conformation of a Major Facilitator Superfamily multidrug/H(+) antiporter provides insights into switching mechanism
por: Nagarathinam, Kumar, et al.
Publicado: (2018)

Computational study of NMDA conductance and cortical oscillations in schizophrenia
por: Kirli, Kübra Komek, et al.
Publicado: (2014)

NMDA-receptor antibodies alter cortical microcircuit dynamics
por: Rosch, Richard E., et al.
Publicado: (2018)

STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons
por: Gruszczynska-Biegala, Joanna, et al.
Publicado: (2020)

Diverse role of NMDA receptors for dendritic integration of neural dynamics
por: Tang, Yuanhong, et al.
Publicado: (2023)

BK channel agonist represents a potential therapeutic approach for lysosomal storage diseases
por: Zhong, Xi Zoë, et al.
Publicado: (2016)

STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons
por: Serwach, Karolina, et al.
Publicado: (2023)

Impaired Collateral Recruitment and Outward Remodeling in Experimental Diabetes
por: van Golde, Jolanda M., et al.
Publicado: (2008)

Outward Bound Lessons to Live a Life of Leadership
por: Brown, Mark
Publicado: (2019)

The Outward Projection of Retinal Images and Its Bearing on Shooting
por: Berry, Geo. A.
Publicado: (1913)

Institutional distance and Turkey’s outward foreign direct investment
por: Heavilin, Jason, et al.
Publicado: (2020)

Antecedents and Consequences of Outward Emotional Reactions in Table Tennis
por: Fritsch, Julian, et al.
Publicado: (2020)

Tunisian revolution and the demand of healthcare in psychiatry outward department
por: Regaya, M., et al.
Publicado: (2021)

Spontaneous Transient Outward Currents Arise from Microdomains Where BK Channels Are Exposed to a Mean Ca(2+) Concentration on the Order of 10 μM during a Ca(2+) Spark
por: ZhuGe, Ronghua, et al.
Publicado: (2002)

Local activity in dendrites controls STDP by altering NMDA receptor kinetics
por: Rikhye, Rajeev V, et al.
Publicado: (2013)

Lack of the Actin Capping Protein, Eps8, Affects NMDA-Type Glutamate Receptor Function and Composition
por: Morini, Raffaella, et al.
Publicado: (2018)

The NMDA receptor partial agonist d-cycloserine does not enhance motor learning
por: Günthner, Jan, et al.
Publicado: (2016)

Supply-demand balance in outward-directed networks and Kleiber's law
por: Painter, Page R
Publicado: (2005)

Femoral shaft osteotomy for obligate outward rotation due to SCFE
por: Stevens, Peter M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_f4f1au71nnv4ldgd4k08i6grg1