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Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster
The relationships of higher order chromatin organization to mammalian gene expression remain incompletely defined. The human Growth Hormone (hGH) multigene cluster contains five gene paralogs. These genes are selectively activated in either the pituitary or the placenta by distinct components of a r...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889918/ https://www.ncbi.nlm.nih.gov/pubmed/26893355 http://dx.doi.org/10.1093/nar/gkw090 |