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Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster

The relationships of higher order chromatin organization to mammalian gene expression remain incompletely defined. The human Growth Hormone (hGH) multigene cluster contains five gene paralogs. These genes are selectively activated in either the pituitary or the placenta by distinct components of a r...

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Detalles Bibliográficos
Autores principales:	Tsai, Yu-Cheng, Cooke, Nancy E., Liebhaber, Stephen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889918/ https://www.ncbi.nlm.nih.gov/pubmed/26893355 http://dx.doi.org/10.1093/nar/gkw090

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