A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes

The transcriptional shift from repression to activation of target genes is crucial for the fidelity of Notch responses through incompletely understood mechanisms that likely involve chromatin-based control. To activate silenced genes, repressive chromatin marks are removed and active marks must be a...

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Detalles Bibliográficos
Autores principales: Oswald, Franz, Rodriguez, Patrick, Giaimo, Benedetto Daniele, Antonello, Zeus A., Mira, Laura, Mittler, Gerhard, Thiel, Verena N., Collins, Kelly J., Tabaja, Nassif, Cizelsky, Wiebke, Rothe, Melanie, Kühl, Susanne J., Kühl, Michael, Ferrante, Francesca, Hein, Kerstin, Kovall, Rhett A., Dominguez, Maria, Borggrefe, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889922/
https://www.ncbi.nlm.nih.gov/pubmed/26912830
http://dx.doi.org/10.1093/nar/gkw105

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