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C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair
Non-homologous end joining is a ligation process repairing DNA double strand breaks in eukaryotes and many prokaryotes. The ring structured eukaryotic Ku binds DNA ends and recruits other factors which can access DNA ends through the threading of Ku inward the DNA, making this protein a key ingredie...
Autores principales: | McGovern, Stephen, Baconnais, Sonia, Roblin, Pierre, Nicolas, Pierre, Drevet, Pascal, Simonson, Héloïse, Piétrement, Olivier, Charbonnier, Jean-Baptiste, Le Cam, Eric, Noirot, Philippe, Lecointe, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889933/ https://www.ncbi.nlm.nih.gov/pubmed/26961308 http://dx.doi.org/10.1093/nar/gkw149 |
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