Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks

Alternative splicing is regulated by multiple RNA-binding proteins and influences the expression of most eukaryotic genes. However, the role of this process in human disease, and particularly in cancer, is only starting to be unveiled. We systematically analyzed mutation, copy number, and gene expre...

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Detalles Bibliográficos
Autores principales: Sebestyén, Endre, Singh, Babita, Miñana, Belén, Pagès, Amadís, Mateo, Francesca, Pujana, Miguel Angel, Valcárcel, Juan, Eyras, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889968/
https://www.ncbi.nlm.nih.gov/pubmed/27197215
http://dx.doi.org/10.1101/gr.199935.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889968/
https://www.ncbi.nlm.nih.gov/pubmed/27197215
http://dx.doi.org/10.1101/gr.199935.115

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