Cargando…
Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks
Alternative splicing is regulated by multiple RNA-binding proteins and influences the expression of most eukaryotic genes. However, the role of this process in human disease, and particularly in cancer, is only starting to be unveiled. We systematically analyzed mutation, copy number, and gene expre...
Autores principales: | Sebestyén, Endre, Singh, Babita, Miñana, Belén, Pagès, Amadís, Mateo, Francesca, Pujana, Miguel Angel, Valcárcel, Juan, Eyras, Eduardo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889968/ https://www.ncbi.nlm.nih.gov/pubmed/27197215 http://dx.doi.org/10.1101/gr.199935.115 |
Ejemplares similares
-
A semi-supervised approach uncovers thousands of intragenic enhancers differentially activated in human cells
por: González-Vallinas, Juan, et al.
Publicado: (2015) -
Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer
por: Sebestyén, Endre, et al.
Publicado: (2015) -
Leveraging transcript quantification for fast computation of alternative splicing profiles
por: Alamancos, Gael P., et al.
Publicado: (2015) -
Predictive Models of Gene Regulation from High-Throughput Epigenomics Data
por: Althammer, Sonja, et al.
Publicado: (2012) -
Mutations primarily alter the inclusion of alternatively spliced exons
por: Baeza-Centurion, Pablo, et al.
Publicado: (2020)